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The IARC TP53 Mutation Database

The IARC TP53 Mutation Database compiles all TP53 gene mutations identified in human cancers and cell lines that have been reported in the peer-reviewed literature since 1989. The following datasets are available:

  • TP53 somatic mutations in sporadic cancers
  • TP53 germline mutation in familial cancers
  • Common TP53 polymorphisms identified in human populations
  • Functional properties of P53 mutant proteins
  • TP53 gene status in human cell-lines.

The project website can be found at http://www-p53.iarc.fr/index.html

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